Journal of AdvancedMedical and Dental Sciences Research

Background:Flexible bronchoscopy is a medical procedure used to examine the airways of the lungs using a thin, flexible tube with a light and camera attached to it. The present study was conducted to assess midazolam with fentanyl-midazolam combination during flexible bronchoscopy. Materials & Methods:60 patients undergoing flexible bronchoscopy of both genderswere divided into three groups. Group I received midazolam, group II fentanyl-midazolam and group III placebo. Vitals signs including heart rate, respiratory rate, blood pressure, and oxygen saturation (SpO2) were recorded. Ramsay Sedation Scale was also assessed during the procedure. The composite score of patient-reported tolerance, satisfaction were recorded. Results: There were 12 males and 8 females in group I, 11 males and 9 females in group II and 10 males and 10 females in group III. The mean height was 165.2 cm, 164.2 cm and 161.5 cm in group I, II and III respectively. The mean weight was 52.4 kgs, 53.6 kgs and 55.1 kgs. The mean BMI was 20.4 kg/m2, 19.5 kg/m2and 20.2 kg/m2 in group I, II and III respectively. The mean HADS- A score was 7.2, 9.1 and 8.6 in group I, II and III respectively. The difference was significant (P< 0.05). The mean Ramsay sedation score was 2.1, 2.4 and 2.0. Patient satisfaction composite score was 54.2, 55.6 and 43.8, physician-reported feasibility composite score was 25.4, 26.2 and 24.1 and rescue doses was 1, 0 and 4 in group I, II and III respectively. Conclusion: When compared to midazolam alone, conscious sedation with a fentanyl-midazolam combination can lead to higher patient and operator satisfaction.