Journal of AdvancedMedical and Dental Sciences Research

Background:Chronic renal failure (CRF) can cause abnormalities in the elemental status of physiological fluids and tissues, which can result in either an excess or a shortage of these nutrients. The present study was conducted to assess serum zinc and magnesium level in patients with chronic renal failure patients. Materials & Methods: 64 chronic renal failure patients of both genders were selected in this study. 2 groups were made. Group I had CRF patients undergoing hemodialysis and group II hadhealthy control. Serum magnesium and zinc level were studied. Results: Group I had 38 males and 26 females and group II had 34 males and 30 females. The mean magnesium level before dialysis in group I was 2.90 µg/L and after treatment was 1.86 µg/L. In group II, the mean magnesium level before dialysis was 2.08 µg/L and after was 1.92 µg/L. The mean zinc level before dialysis in cases was 278.2 µg/L and after was 170. µg/L. In group II, the mean zinc level before dialysis was 298.6 µg/L and after was 218.4 µg/L. The difference was significant (P< 0.05). Conclusion: In patients with chronic renal failure, level of zinc and magnesium falls after dialysis.