Journal of AdvancedMedical and Dental Sciences Research

Background: Osteoporosis, a prevalent skeletal condition, is marked by diminished bone strength and heightened susceptibility to fractures. Therapies for osteoporosis have demonstrated efficacy in enhancing bone strength and mitigating the risk of fractures. The primary medications employed for osteoporosis treatment include bisphosphonates, along with supplements containing Calcium and Vitamin D. However, there exist clinical challenges in effectively utilizing bisphosphonates, Calcium, and Vitamin D supplements for the treatment of osteoporosis. Methods: The administration of oral bisphosphonates, Calcium, and Vitamin D supplements for osteoporosis treatment involves the careful selection of suitable patients for initiating therapy. To assess the effectiveness of these treatments, a comparative analysis between two drugs was conducted, employing paired and unpaired T-tests. Calculations were performed to compare the conditions before and after treatment, providing insights into the impact of the therapeutic approach.Results: A total of 240 patients were enrolled in the study, with the majority falling in the age range of 36-60 years. Among these adults, 138 (57.50%) were males, and 102 (42.50%) were females. The study involved a division where 50% of the patients received Ibandronic acid, and the remaining 50% were treated with calcium and Vitamin D. Conclusion: The study concludes that patients exposed to Ibandronic acid exhibit more significant improvements in bone mineral density (BMD) compared to those exposed to calcium and Vitamin D. Additionally, the research findings suggest that oral bisphosphonates, such as Ibandronic acid, demonstrate greater effectiveness in enhancing BMD for osteoporosis when compared to calcium supplements.