Journal of AdvancedMedical and Dental Sciences Research

Background:Subclinical hypothyroidism (SCH) is identified when peripheral thyroid hormone levels fall within the standard reference range, while serum thyroid-stimulating hormone (TSH) levels show a slight elevation. Thyroid hormone plays a crucial role in governing various cellular and molecular processes, influencing nearly every cell and organ in the body, including the heart. Our objective was to investigate the occurrence of left ventricular diastolic dysfunction among individuals with subclinical hypothyroidism.Methods:A hospital-based study was conducted on individuals with subclinical hypothyroidism (SCH), meeting specified inclusion and exclusion criteria, who were attending the outpatient department (OPD) or admitted to the inpatient department (IPD).Results: The average TSH levels in cases of subclinical hypothyroidism are 7.51±1.57 mU/L, with mean Free T4 levels at 1.67±0.38 pmol/L and mean Free T3 levels at 4±0.81 pmol/L. Additionally, the mean left ventricular end-diastolic diameter (LVEDD) is 47.66±3.24 mm, mean left ventricular end-systolic diameter (LVESD) is 30.618±5.7 mm, diastolic interventricular septum thickness (Diastolic IVST) is 9.8±1.59 mm, diastolic left ventricular posterior wall thickness (Diastolic LVPWT) is 9.8±1.8 mm, and left ventricular mass (LVM) is 35.91±5.7 mm.Conclusion:Newly identified subclinical hypothyroidism is frequently linked to cardiovascular changes. Timely diagnosis and correction of hypothyroidism are imperative to minimize the early impact on the cardiovascular system.