Journal of AdvancedMedical and Dental Sciences Research

Background: Diabetes mellitus (DM) is a prevalent metabolic disorder marked byhyperglycemia and metabolic abnormalities of carbohydrates, proteins, and lipids. The present study was conducted to assess thyroid function in type 2 diabetes mellitus patients without nephropathy and with nephropathy. Materials & Methods: 60 type II diabetes mellitus patients of both genderswere divided into 2 groups of 30 each. Group I were type II DM patients without diabetic nephropathy and group II were type II DM patients with diabetic nephropathy. Assessment of thyroid level was performed. Results: Group I had 16 males and 14 females and group II had 15 males and 15 females. Thyroid level was normal in 23 in group I and 14 in group II, low T3 syndrome in 4 in group I and 8 in group II, subclinical hypothyroidism in 2 in group I and 5 in group II and overt hypothyroidism in 1 in group I and 3 in group II. The difference was significant (P< 0.05). Conclusion: The prevalence of thyroid dysfunction was higher in patients with diabetic nephropathy. Therefore, in order to enhance quality of life and lower morbidity, thyroid hormone monitoring in type 2 diabetics and diabetic nephropathy is necessary.