Journal of AdvancedMedical and Dental Sciences Research

Background: Hyperosmolar hyperglycemic state (HHS) is a complication of diabetes mellitus in which high blood sugar results in high osmolarity without significant ketoacidosis. The present study assessed MRI findings in patients with hyperosmolar hyperglycemic state. Materials & Methods: 65 patients of hyperosmolar hyperglycemic state of both genders were assessed for serum osmolality and blood urea nitrogen. All the patients underwent MRI on a 1.5 Tesla scanner. Results: Out of 65 patients, males were 30 and females were 35. Clinical findings were focal motor seizures in 23, multiple myoclonic jerks in 22, generalized tonic clonic seizures in 10 and complex partial seizures in 10 cases. The mean Na+/K+ level was 135.2/4.2 mmol/l, serum osmolarity was 302.4 mOsm/Kg, blood glucose level found to be 474.2 mg/dl and HbA1C level was 13.5%. The difference was non- significant (P> 0.05). Conclusion: Clinical findings were focal motor seizures, multiple myoclonic jerks, generalized tonic clonic seizures and complex partial seizures.