Journal of AdvancedMedical and Dental Sciences Research

Aim: A case-control study to detect cognitive impairment in Type 2 diabetes mellitus using selected auditory and visual response times under acute mental stress. Methods: The Department of Physiology conducted this prospective observational research. The research comprised 90 participants between the ages of 35 and 60. Each participant provided informed consent. They were split into two groups. Group 1 consisted of 40 randomly selected diagnosed patients with Type 2 DM with a duration of at least two years. The second group consisted of 45 age and gender-matched controls. The MMSE was used to measure the overall cognitive function of these groups. In these groups, simple and choice auditory and VRTs were evaluated at rest and under acute mental stress to assess cognitive performance. The standard deviation acquired during the pilot research was used to assess the dependability of the response timing. Results: The Type 2 DM group had a mean age of 46.33±5.67 years, whereas the control group had a mean age of 44.98±5.73 years. There was a statistically significant difference between weight and BMI. Tables 2 and 3 indicate a substantial difference in ART and VRT in Type 2 DM and controls, both basic and choice. These RTs rose much more under diabetes-related mental stress. There was a significant difference in ART and VRT, both simple and choice, during rest and mental stress, and that these RTs were longer in Type 2 DM as compared to controls. Conclusion: We may infer that mental stress in Type 2 DM does influence cognition, with the degree of impairment perhaps correlated with the difficulty of the task (mental stress) and the prevalence of central nerve deficits and peripheral nerve deficits observed as side manifestations of Type 2 DM.