Journal of AdvancedMedical and Dental Sciences Research

Periapical surgery is the preferred treatment of choice in failed root canal therapy, chronic periapical lesion, persistent apical periodontitis, etc., when conventional treatment modalities fail. Moreover after periapical curettage the lesions underwent slow healing giving a dilemma of unsuccessful periapical surgeries.This study was thus undertaken to evaluate the use of a novel autologous platelet concentrate‑concentrated growth factor (CGF) in periapical defects to ensure better healing of these lesions which were otherwise left ungrafted for the body’s own immune response to heal. IOPAR & PAI score were done at baseline & at 6 months to evaluate the efficacy of CGF as a graft material in peri apical defects.in Group A and without graft in Group B. However, the result showed complete healing of the hard and soft‑tissue lesions that conform to achieving repair and regeneration at a rapid rate in periapical lesions in Group A as compared to Group B.