Journal of AdvancedMedical and Dental Sciences Research

Background: Hypertension is a condition marked by elevation in the systolic blood pressure (SBP) and/or diastolic blood pressure (DBP). The present study was conducted to assess serum magnesium levels in hypertension and its association with cardiovascular changes. Materials & Methods: 110 patients of essential hypertension of both genders. Patients were divided into two groups. Group I had patients with systolic BP of 140-159 mm Hg or diastolic BP of 90-99 mm Hg and group II, patients with systolic BP of ≥160 mm Hg or diastolic BP of ≥100 mm Hg. Assessment of serum magnesium, calcium, potassium and sodium and creatinine levels were measured by isotope dilution mass spectrometry. Ventricular hypertrophy was determined using Sokolow-Lyon criteria by performing electrocardiography. Results: Group I had 35 males and 20 females and group II had 22 males and 33 females. The mean calcium was 8.21 in group I and 8.69 in group II, sodium was 134.2 in group I and 139.5 in group II, magnesium was 2.31 in group I and 1.80 in group II, potassium was 4.19 in group I and 4.06 in group II and creatinine was 0.82 in group I and 0.94 in group II. The difference was non- significant (P> 0.05). Conclusion: The level of magnesium level decreased as the grade of hypertension increased.