Journal of AdvancedMedical and Dental Sciences Research

Aim: Histopathological study of neoplastic lesions of thyroid in a tertiary care centre. Methods: The Department of Pathology conducted this retrospective analysis. Thyroidectomy specimens from lobectomy, partial thyroidectomy, subtotal thyroidectomy, and complete thyroidectomy were used in this investigation. FNAC evaluated each patient before to surgery. Histopathological report forms included detailed information on age, gender, clinical data (hypothyroid, hyperthyroid, and euthyroid), pertinent investigations such as Fine Needle Aspiration Cytology, USG reports, thyroid scan, and operation. Results: The total number of thyroid specimens received was 140. Neoplastic lesions, mostly adenomas and carcinomas, were detected in 120 instances (85.71 percent) of thyroidectomy specimens. There were 95 (79.17 percent) female cases and 25 (20.83 percent) male cases, for a female:male ratio of 3.8:1. Adenomas were found in 33 of the 120 neoplastic tumours (27.5 percent of the neoplastic category). There were 26 instances of follicular adenoma and 7 cases of Hurthle cell adenoma identified, accounting for 17.5 percent and 5.83 percent of all neoplastic thyroid lesions, respectively. Thyroid cancer accounted for 71.67 percent of all neoplastic lesions. Papillary carcinoma was the most prevalent malignant tumour in this research, accounting for 70% (81.39%) of all malignant tumours. This investigation found 10 instances of follicular carcinoma and 6 cases of medullary carcinoma, accounting for 6.67 percent and 3.33 percent of all malignant neoplasms, respectively. Conclusion: females accounted for 79.17 percent of patients with neoplastic thyroid lesions, and the frequency increased with age. Papillary carcinoma was the most prevalent kind of thyroid cancer, accounting for 58.33% of all thyroid malignancies, whereas follicular adenoma was the most common benign tumour.