Journal of AdvancedMedical and Dental Sciences Research

Background: Functional endoscopic sinus surgery (FESS) is today the most common type of surgery for chronic rhinosinusitis. The present study was conducted to compare dexmedetomidine and magnesium sulphate (MgSO4) for controlled hypotension in FESS. Materials & Methods: 64 patients belonging to the American Society of Anesthesiologists' Physical Status (ASA-PS) grades I and II between 18–60 years were divided into 2 groups of 32 each. Group I received dexmedetomidine 1 μg/kg over 10 min followed by infusion at 0.2 to 0.7 μg/kg/hour and group II patients received MgSO4 40 mg/kg over 10 min followed by an infusion at 10 to 15 mg/kg/hour. Results: Group I had 20 males and 12 females and group II had 18 males and 14 females. Duration anaesthesia was 90.3 minutes in group I and 110.4 minutes in group II, duration of surgery was 75.4 minutes in group I and 92.6 minutes in group II, mean time to achieve target MAP was 10.2 minutes in group I and 23.1 minutes in group II. Bleeding score 2 or less was seen in 25 minutes in group I and 6 minutes in group II, >2 was seen in group I and 7 and 24 in group II, satisfaction score 2 or less was seen minutes in 4 group I and 27 in group II, >2 was seen in 28 group I and 5 group II. The difference was significant (P< 0.05).