Journal of AdvancedMedical and Dental Sciences Research

Background: Hemodialysis is a frequent interventional treatment method because of high prevalence of chronic kidney disease. The present study was conducted to assess serum magnesium and zinc level in patients with chronic renal failure. Materials & Methods: 72 chronic renal failure patients of both genders were enrolled. 2 groups were prepared. Group I had CRF patients undergoing hemodialysis patients and group II had control subjects. Serum samples were separated and analysed using atomic absorption technique and according to the instruction of apparatus. Results: Group I had 42 males and 30 females and group II had 45 males and 27 females. The mean zinc level before dialysis in cases was 281.6 µg/L and after was 172.3 µg/L. In group II, the mean zinc level before dialysis was 290.4 µg/L and after was 210.2 µg/L. The mean magnesium level before dialysis in cases was 2.9 µg/L and after was 1.8 µg/L. In group II, the mean magnesium level before dialysis was 2.04 µg/L and after was 1.92 µg/L. The difference was significant in group I (P< 0.05). Conclusion: Level of zinc and magnesium fall significantly after dialysis especially in patients with chronic renal failure, hence there is need to assess the level of these trace elements periodically.