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Volume 9 Issue 2 (February, 2021)

Original Articles

Assessment of adverse events associated with apheresis procedures
Dr. Tarun Kumar, Dr. Seema Solanki, Dr. Manav Vadhera, Dr. Jessica Kaushal, Dr Neeeaj Joshi

Background: Over decades, increased demand of platelet transfusions for patients with various medical and surgical diagnoses led to accelerated usage of technologically advanced “Apheresis” for platelet concentrates which is conducted under the transfusion medicine specialist’s supervision in special dedicated areas. Hence; the present study was conducted with the aim of assessing adverse events associated with apheresis procedures. Materials & methods: A total of 500 apheresis procedures were analysed in the present study. Complete demographic details of all the patients were obtained. A Performa was designed and complete details were recorded in it. All adverse events were recorded by the staff. The adverse events occurring during or after the procedures were classified as vascular injuries (VIs), citrate reaction (CR), presyncopal/syncopal (PS/S), and PS + CR both. All the results were recorded and analysed using SPSS software. Results: Overall, vascular injuries were seen in 4 patients while citrate reaction was seen in 3 patients. Among vascular injuries, 2 adverse reactions were seen during procedure while the remaining 2 cases were seen after procedure. Conclusion: Apheresis donations have very less fraction of acute reaction rates which are relatively mild and easily treated.

 
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