Journal of AdvancedMedical and Dental Sciences Research

Background: Acne is an inflammatory disorder of pilosebaceous units and is prevalent in adolescence. Decreased serum zinc levels have been reported in number of cutaneous disorders by some investigators, while others have refuted these findings. Hence; under the light of above mentioned data, the present study was undertaken for assessing serum zinc levels in acne patients. Materials & methods: A total of 50 acne patients and 50 healthy controls were enrolled. Complete demographic and clinical data of all the patients was recorded. All the acne patients were divided on the basis of severity into mild, moderate and severe cases. Blood samples were obtained from all the patients and were sent to laboratory where an auto-analyser was used for evaluation of serum zinc levels. Results: Mean serum zinc levels among the patients of the acne group and control group was 83.12 µg/dL and 84.68 µg/dL respectively. While comparing statistically, non-significant results were obtained. Mean serum zinc levels among the patients with mild, moderate and severe acne were 89.23 µg/dL, 79.12 µg/dL and 72.36 µg/dL respectively. While comparing statistically, significant results were obtained. Conclusion: Serum zinc levels decrease significantly with increasing severity grades among acne patients.