Oral submucous fibrosis (OSMF) is a premalignant disorder which is most commonly associated with the chew¬ing of areca nut (betel nut). Oral submucous fibrosis is diagnosed based on clinical symptoms and confirmed by histopathological report. Based on clinical symptoms and histopathology changes this condition is categorized in four stages. The initial presentation of OSMF is inflammation. Inflammation is followed by hypovascularity and fibrosis visible as blanching of the oral mucosa with a marble-like appearance. Blanching may be localized, diffuse, or reticular. In some cases, small vesicles may develop that rupture and form erosions. In the later advanced stage of OSMF, a fibrous band that restricts mouth opening (trismus) is characteristic. It causes further problems in oral hygiene, speech, mastication, and possibly swallowing. Development of fibrous bands in the lip leads to thickening and rubbery appearance. Management of this premalignant condition is mainly based on the level of disease. Most commonly favored line of treatment is Medical treatment (Non Surgical ).
Keywords – Oral Submucous fibrosis, Premalignant condition, Oxitard , Aloe vera, Pentoxifylline, Spirulina.