Background: Xerostomia is most frequently associated with the altered salivary gland function. The present study was conducted to assess management of xerostomia among denture wearer. Materials & Methods: The present study was conducted on 120 edentulous patients of both genders. Patients were divided into 2 groups. Group I patients was given Pilocarpine and group II were given bethanechol for a week’s course. In all patients, whole resting saliva (WRS) and whole stimulated saliva (WSS) were collected and compared. Results: Baseline salivary value was 0.52 mg/min in group I and 0.58 mg/min in group II. Whole resting saliva in group I was 0.76 mg/min and in group II was 0.71 mg/min. Whole stimulated saliva was 1.89 mg/ min in group I and 1.54 mg/ min in group II. The difference was significant (P< 0.05). Conclusion: Authors found that Pilocarpine is an effective sialagogue agent that can be safely used in xerostomic edentulous patients.
Key words: Pilocarpine, sialagogue, Xerostomia.