Background: Postoperative pain control is frequently performed with the administration of short-acting local anesthetic and oral analgesics. The present study compared the efficacy of bupivacaine versus lignocaine local anesthetic agent in preventing post- operative pain in single sitting endodontic treatment. Materials & Methods: The present study was conducted on 80 patients requiring endodontic treatment of maxillary anterior teeth of both genders. Patients were divided into 2 groups of 40 each. Group I patients was administered lidocanine (2% with 1:100000 epinephrine) local anesthesia and the group II with bupivacaine (0.5% without epinephrine). Results: The mean VAS before treatment in both group was 6, after 2 hours was 5.1 in group I and 5.1 in group II, at 6 hours was 4.9 in group I and 4.6 in group II, at 8 hours was 4.5 in group I and 3.2 in group II, at 12 hours was 3.8 in group I and 2.8 in group II, at 24 hours was 2.9 in group I and 2.2 in group II, at 48 hours was 2.5 in group I and 1.4 in group II. The difference was significant (P< 0.05). Conclusion: Bupivacaine 0.5% used in infiltration anesthesia could be more effective in reduction or prevention of post-operative endodontic pain compared with lidocaine.
Key words: Anesthesia, Bupivacaine, lignocaine.