Journal of AdvancedMedical and Dental Sciences Research

Introduction: The aim of this study is to determine the H. Pylori status of patients with PPD so that decision makers will use the information for priority setting and make decisions based on existing evidence. Materials and Methods: This Retrospective observational study was conducted in 70 cases of DU perforation with peritonitis who presented to the casualty. All the charts of the patients with perforation peritonitis were analyzed from the medical record department for operative notes. Patient details like age, sex, detailed history with emphasis on previous history of acid peptic disease, past medical history, medical treatment for acid peptic disease and physical examination were recorded. Emergency laparotomy was done in all cases of DU perforation. Results: One minute rapid urease test was positive in a total of 45 patients (64.2%) and majority of the cases reported was in the fifth decade of the life followed by fourth decade group. The distribution of cases among gender is shown in table no.2 depicting majority of them being male 84% of cases. Conclusion: The present study shows that the risk of developing H. pylori related duodenal ulcer perforation is strongly increased in those patients where the organism is detected by rapid urease test in the duodenum.