Journal of AdvancedMedical and Dental Sciences Research

Background:Lichen planus is a chronic inflammatory condition that affects the skin, mucous membranes, hair, and nails.The present study was conducted to assess uric acid in patients with lichen planus. Materials & Methods:58 cases of lichen planus of both genderswere put in group I and healthy control in group II. Five milliliters of venous blood sample were collected in each group after 12 h of fasting. Serum UA was assayed using Coralab 3000 semiautoanalyser, by uricase method. Results: Group I had 18 males and 40 females and group II had 29 males and 29 females. The mean serum uric acid in group I was 3.52 mg/dl and in group II was 3.96 mg/dl. The difference was significant (P< 0.05). Conclusion: A drop in serum UA levels is linked to LP. UA has the potential to be a valuable biomarker of LP's antioxidant status for monitoring and therapy planning.