Journal of AdvancedMedical and Dental Sciences Research

Background:Osteoporotic fractures in the third trimester of pregnancy or in the early postpartum period can occur in premenopausal women with pregnancy and lactation-related osteoporosis. The present study was conducted to assess fracture incidence in patients with pregnancy and lactation osteoporosis (PLO). Materials & Methods:128postpartum women with pregnancy and lactation osteoporosis (PLO) were enrolled. Parameters such as type of fracture bone involved and osteoporosis management given were recorded. Results: Location was lumbar vertebra in 10, lumbar spine and pelvis in 24, rib in 12, coccyx in 4, sacrumin 3, femur in 2, sternum and thorax in 15, and foot and toe in 6 patients. The difference was significant (P< 0.05). Treatments for osteoporosis wereCinacalcet in 10, Ibandronatein 15, Pamidronate in 21, Etidronate in 5, Alendronate in 7 and Denosumab in 8 patients. The difference was significant (P< 0.05). Conclusion: Maximum women with pregnancy and lactation osteoporosis had fractures of lumbar spine and pelvis, rib, and lumbar vertebra.