Journal of AdvancedMedical and Dental Sciences Research

Background: In India, 20 out of every 100,000 women will be diagnosed with breast cancer, which ranks as the second most frequent cancer after cervical cancer. The present study evaluated the histomorphological spectrum of breast lesions in young females. Materials & Methods:280 females <30 years old with breast lesions were enrolled. The site of breast lesions were recorded. Histopathological examination was performed by standard procedures using 10% formalin, paraffin embedding and staining by H&E methods. Results: Benign breast lesions found to be breast abscess in 92, accessory breast in 2, fibroadenoma breast in 32, fibroadenomatosis in 18, benign breast lesion in 56, lipoma in 30, granulomatous lesion in 8, benign fibrous histiocytoma in 6 and tubular adenoma in 6 cases. The difference was significant (P< 0.05). Malignant lesions were invasive ductal carcinoma breast in 11 and proliferative breast disease with atypia in 19 cases. The difference was significant (P< 0.05). The site of breast lesion was upper outer Quadrant in 120, lower Outer Quadrant in 52, Upper Inner Quadrant in 48, Lower Inner Quadrant in 24, Central Quadrant in 20 and Whole Quadrant in 16 cases. The difference was significant (P< 0.05). Conclusion: The majority of cases had benign lesions rather than malignant ones. Benign breast lesions and breast abscesses were frequent lesions. The upper outside quadrant was the common site.