Journal of AdvancedMedical and Dental Sciences Research

Background:Acne Vulgaris stands out as the prevailing skin disorder involving the pilosebaceous unit, marked by an overproduction of sebum, heightened follicular epidermal growth, inflammation, and the activity of Propionibacterium acnes. It impacts roughly 80% of teenagers, giving rise to substantial psychological and social repercussions, along with physical disability. The objective is to assess the prescription patterns and the underlying reasoning behind drug therapy for acne vulgaris.Methods:In this prospective, hospital-based, observational study, demographic information, disease-related data, and details concerning the drug therapy of the subjects were assessed, taking into account the specified inclusion and exclusion criteria.Results:Analysis was conducted on the prescription data of 173 patients, revealing that 40% were males with an average age of 21.94±0.3 years. Among the four grades of Acne Vulgaris, Grade II was the most prevalent at 56.17%, followed by Grade I (23.58%), Grade III (15.87%), and Grade IV (4.35%). A total of 128 topical drugs were prescribed, with the most common being Tretinoin alone (18.46%), a combination of Tretinoin and Clindamycin (16.12%), Benzoyl Peroxide (14.45%), and Clindamycin alone (10.51%). For systemic use, 49 drugs were prescribed, with Doxycycline (50.1%), Azithromycin (39.7%), Isotretinoin (8.12%), and Erythromycin (2.08%) being the primary choices.Conclusion:The majority of prescriptions demonstrated rationality, minimizing the likelihood of polypharmacy.