Journal of AdvancedMedical and Dental Sciences Research

Background:Stroke stands as the third leading cause of death, accounting for 9% of all fatalities in industrialized nations, and remains a major contributor to global disability. The carotid intima-medial thickness (IMT) has emerged as a reliable independent indicator of cardiovascular conditions. C-reactive protein (CRP) has been established as a significant contributing factor to cardiovascular disease. The link between CRP and stroke becomes more substantial when coupled with an elevated carotid IMT.Methods:This study is a prospective cross-sectional investigation conducted over a one-year period, involving a cohort of 200 patients.Results:A total of 200 participants were included in the study. The mean levels of carotid intimal thickness and C-reactive protein were 0.823 ± 0.25 mm and 7.867 ± 3.76 mg/dl, respectively. Among the participants, 100 out of 200 reported carotid intima medial thickness exceeding 0.8 mm. There was a highly significant association between carotid intima thickness and patient outcomes (p < 0.003), with 65% of participants reporting CRP levels greater than 6 mg/dl (p < 0.001). Additionally, there was a significant correlation between carotid medial thickness and C-reactive protein levels (p < 0.001).Conclusion:Supplementing conventional risk factors with the inclusion of C-reactive protein (CRP) and carotid intima-medial thickness demonstrated a modest improvement in predicting cerebrovascular accidents. Regular monitoring of identified risk factors in high-risk individuals, along with broader acceptance of the expected course of treatment in tertiary centers equipped with emergency intensive care units, has the potential to reduce episodes leading to morbidity and mortality.