Journal of AdvancedMedical and Dental Sciences Research

Gallstones are indicative of a failure in the regulation of certain biliary constituents, primarily cholesterol and calcium salts, leading to their precipitation. In the pathogenesis of gallstones, the presence of biliary sludge is crucial. Biliary sludge is characterized by a mixture of cholesterol crystals, calcium bilirubinate granules, and a mucin gel matrix.The collection of general patient information, including their name, age, gender, religion, occupation, socio-economic status, and address, was carried out. Detailed medical histories were obtained, focusing on the duration of right upper quadrant pain or epigastric pain, its periodicity, whether it worsened after consuming fatty meals, and if it was alleviated by oral or parenteral analgesics. Among the patients, 32 presented with both nausea and abdominal pain, while 156 experienced vomiting. A larger group, consisting of 188 patients, had both nausea and vomiting. Additionally, jaundice was observed in 66 patients. These clinical findings provide insights into the presentation and associated symptoms of individuals with gallstone-related conditions.