Journal of AdvancedMedical and Dental Sciences Research

Background: The present study was conducted for evaluated serum adiponectin levels in patients with chronic liver disease. Materials & methods: A total of 100 patients with confirmed diagnosis of chronic liver disease were included in the present study. Complete demographic details of all the patients were obtained. A questionnaire was framed and detailed knowledge of radiographic investigations was recorded separately. Another set of age-and gender-matched 100 subjects which came for routine check-up were taken as healthy controls. Blood samples were obtained from all the patients and auto-analyser was used for evaluation of serum adiponectin levels. All the results were recorded in Microsoft excel sheet and were subjected to statistical analysis using SPSS software. Results: Mean adiponectin levels among patients of CLD group and control group was 18.6 µg/mL and 8.5µg/mL respectively. While comparing the adiponectin levels among the patients of CLD group and control group, significant results were obtained. Also, while correlating Adiponectin levels with BMI, significant results were obtained. Conclusion: Serum adiponectin levels were significantly altered among CLD patients highlighting their role in the pathogenesis of the disease.