Journal of AdvancedMedical and Dental Sciences Research

Background: The present study was conducted for assessing the microbiological profile and antibiotic susceptibility pattern of Gram-positive isolates. Materials & method: A total of 500 patient samples were evaluated in the present study. Among these tested samples, gram positive isolates were identified and separately analysed. The patient samples were processed using standard laboratory techniques and were further cultured overnight on Columbia sheep blood agar (CBA) (BioMérieux, France) and on MacConkey's agar (HIMedia, India). Further, organism identification and antibiotic susceptibility test was done using the automated system. The antibiotic susceptibility testing was reported. Results: Out of 186 staphylococcus aureus positive cases, ciprofloxacin, linezolid and vancomycin resistance was seen in 85, 77, 67, 84 and 71 cases respectively. Out of 101 Enterococcus positive cases, ciprofloxacin, linezolid and vancomycin resistance was seen in 39, 25, 24, 20 and 38 cases respectivelyOut of 53 CONS positive cases, ciprofloxacin, linezolid and vancomycin resistance was seen in 30, 28, 32, 19 and 35 cases respectively.Out of 42 Streptococcus spp. positive cases, ciprofloxacin, linezolid and vancomycin resistance was seen in 29, 24, 26, 21 and 25 cases respectively. Conclusion: Continuous and periodic evaluation of microbiological pattern and antibiotic sensitivityis necessary to decrease the potential risks of complications by early institution of appropriate systemic and topical antibiotic alongside mastoid exploration.