Journal of AdvancedMedical and Dental Sciences Research

Background: Hemodialysis is a frequent interventional treatment method because of high prevalence of chronic kidney disease. The present study was conducted to assess serum magnesium and zinc level in patients with chronic renal failure. Materials & Methods: 80 chronic renal failure patients of both genders were enrolled. 2 groups were prepared. Group I had CRF patients undergoing hemodialysis and group II hadhealthy control. Serum samples were studied for magnesium and zinc level. Results: Group I had 45 males and 35 females and group II had 42 males and 38 females. The mean magnesium level before dialysis in group I was 2.81 µg/L and after treatment was 1.92 µg/L. In group II, the mean magnesium level before dialysis was 2.01 µg/L and after was 1.95 µg/L. The mean zinc level before dialysis in cases was 273.2 µg/L and after was 174.5 µg/L. In group II, the mean zinc level before dialysis was 293.7 µg/L and after was 216.4 µg/L. The difference was significant (P< 0.05). Conclusion: The level of zinc and magnesium falls after dialysis especially in patients with chronic renal failure (CRF).