Journal of AdvancedMedical and Dental Sciences Research

Background: Fractures have a high incidence rate in traffic accidents and are one of the three most important complications during accidents. The present study was conducted to compareintravenous ketamine with morphine in pain relief of long bones fractures. Materials & Methods: 64 patients of long bones fractures of both genders were included. Patients were randomly divided into two groups- group Ireceived intravenous (IV) morphine at a dose of 0.1 mg/kg and group II received IV ketamine at a dose of 0.5 mg/kg. Pain severity of the patients was recorded before and 10 minutes after injection based on numeric rating scale. Results: Group I had 20 males and 12 females and group II had 18 males and 14 females. The mean age was 52.8 years in group I and 48.4 years in group II. Fracture site was upper extremity in 14 and 15 and lower extremity in 18 and 17. Pain score beforetreatment was 9.4 and 9.1 and after treatment was 2.7 and 3.0 in group I and II respectively. The difference was significant (P< 0.05). Conclusion: Low dose of ketamine (0.5 mg/kg) results in a significant decrease in the severity of acute pain in patients with fractures of long bones.