Journal of AdvancedMedical and Dental Sciences Research

Background: Hypertension is a disorder of circulatory regulation. Sustained hypertension causes accelerated atherosclerosis with consequent coronary heart disease (CHD), heart failure, and stroke and renal failure. The present study recorded prevalence of microalbuminuria in patients with essential hypertension. Materials & Methods: 94 patients of essential hypertension of both genders were included. Group I comprised of 94 cases of essential hypertension and group II comprised of 94 healthy subjects. Investigations such as blood urea and serum creatinine, plasma glucose – fasting and postprandial, serum electrolytes–sodium and potassium, serum uric acid, serum calcium and phosphatewere carried out. Microalbuminuria was measured in all patients in a 24hours urinary sample. Results: out of 94 patients, males were 62 and females were 32. Out of 94 patients, microalbuminia was present in 36 (38.2%). The mean blood urea (mg/dl) was 28.5 and 22.1, serum creatinine (mg/dl) was 0.89 and 0.72, uric acid (mg/dl) was 4.71 and 3.82, sodium (meq/L) was 142.3 and 138.4, potassium (meq/L) was 4.93 and 3.12, uric acid (mg/dl) was 4.78 and 3.76, serum calcium (meq/L) was 9.24 and 9.15 and serum phosphate (meq/L) was 3.85and 3.32 in group I and group II respectively. Conclusion: Microalbuminuria was seen in a significant number of newly detected and untreatedpatients of essential hypertension.