Journal of AdvancedMedical and Dental Sciences Research

Background: Heparin is a multifaceted compound with anti-inflammatory, anti-allergenic, anti-histaminic, anti-serotonin and anti-proteolytic enzyme properties. The present study compared treatment of burns with heparin and without heparin. Materials & Methods: 90 patients with different degree of burns of both genders were randomly assigned to group I treated with heparin and group II treated with conventional dressings with silver sulfadiazine, intravenous antibiotics, analgesics and intravenous fluids. Results: Group I had 15 males and 30 females and group II had 20 males and 25 females. The cause of burns was suicidal in 20 in group I and 16 in group II, accidental 15 in group I and 20 n group II and homicidal 10 in group I and 9 in group II. The percentage of burn was 5-15% seen 25 in group I and 22 in group II, 16-25% in 13 in group I and 17 in group II, 26-35% seen 7 in group I and 6 in group II. Mean days of hospitalization was 26.5 days in group I and 35.4 days in group II. Complications reported was atelectasis 1 in group I and 3 in group II, aspiration pneumonia 2 in group I and 2 in group II, DVT 1 in group I, septicemia 1 in group II, pulmonary embolism 1 in group I and 2 in group II and UTI 2 in group II. The difference was significant (P< 0.05). Conclusion: Heparin found to be effective as compared in conventional treatment in terms of less complications and less days of hospitalisation.