Journal of AdvancedMedical and Dental Sciences Research

Background: Normally pressures between the middle and outer ear are equalized by the actions of the tensor palati and levator palati muscle contractions and opening of the eustachian tubes during deglutition. The present study was conducted to compare the effects of sevoflurane versus isoflurane on middle ear pressure (MEP). Materials & Methods: 48 children age ranged 6-12 years of both genders were divided into 2 groups of 24 each. Group I received isoflurane and group II received sevoflurane. Tympanometric functions were evaluated using middle ear analyzer to check the standard immitance screening of the ME of patients. Results: Group I had 14 males and 10 females and group II had 12 males and 12 females. The mean weight in group I patients was 34.1 Kg and group II patients was 32.2 kgs, height was 120.4 cm in group I and 118.4 cm in group II, ASA grade I was seen in 13 and II in 11 in group I and grade I in 14 and II in 10 in group II, time of anesthesia was 52.4 minutes in group I and 49.2 minutes in group II and time of surgery was 34.7 minutes in group I and 29.5 minutes in group II. The difference was non- significant (P> 0.05). The mean middle ear pressure at T0 was -18 at T1 was 27, at T2 was 74 and at T3 was 104 in group I. It was -19, 30, 82 and 136 at T0, T1, T2 and T3 respectively in right ear. It was -16, 34, 81 and 113 in group I and -13, 39, 78 and 140 at T0, T1, T2 and T3 respectively in left ear. The difference non- significant (P> 0.05). Conclusion: During isoflurane anesthesia the rise of middle ear pressure was comparatively lower than sevoflurane.