Journal of AdvancedMedical and Dental Sciences Research

Background: Meningitis is defined as infection predominantly involving subarachnoid space, associated with CNS inflammatory process leading to decreased or loss of consciousness, seizures, and raised intracranial pressure.The present study was conducted to assess CRP level in patients with meningitis. Materials & Methods:118 cases of meningitis of both genderswere included. CSF CRP levels were estimated using Beckman Coulter CRP - latex reagent kit on its full automated instrument AU 480. Results: Out of 118 patients, males were 68 and females were 50. The common clinical findings in patients was fever seen in 110, vomiting in 96, seizures in 84, headache in 90 and loss of consciousness in 54. Common types were types were bacterial in 56, tubercular in 30, viralin 14, cryptococcal in 5, scrub typhus in 3 and paraneoplastic in 2 cases. The mean CRP level (mg/dl) bacterial meningitis was 3.01, tubercular was 0.82, in viral was 0.30, in cryptococcal was 0.36, in scrub typhus was 0.28 and in paraneoplasticwas 0.21. Conclusion: Maximum level of CRP was seen in tubercular type of meningitis as compared to other forms.