Journal of AdvancedMedical and Dental Sciences Research

According to the latest WHO reports, 15 million babies are born prematurely every year, which is more than one tenth of the total number of newborns in the world. The incidence of premature birth (PR) globally ranges from 5–18% [15]. The proportion of births with gestational age less than 28 weeks in the world is only 5.2%, but in economically developed countries, more than 45% of perinatal deaths are associated with them [15]. Despite a huge number of scientific studies devoted to methods of predicting, preventing and treating this complication of pregnancy, the number of PRs not only does not decrease, but has a stable tendency to increase [7, 14].