Journal of AdvancedMedical and Dental Sciences Research

Background: Dengue was the second disease after “yellow fever” that was shown to be caused by virus. The present study was conducted to assess renal involvement in children with dengue fever. Materials & Methods: 68 children age ranged 1 year to 12 years of both genders were diagnosed of dengue fever either NS1 positive or antibody IgM positive or both IgM and IgG positive. +e disease severity was classified according to the World Health Organization criteria. Renal manifestations were divided into AKI groups using pRIFLE criteria. Results: Out of 34 patients with dengue fever, 4 had renal involvement, out of 20 cases of dengue haemorrhagic fever, 5 had renal involvement, out of 14 cases of dengue shock syndrome, 2 had renal involvement. The mean serum creatinine (μmol/L) level was 180 and 90.2, serum Na (mmol/L) was 132.4 and 132.1, serum K (mmol/L) was 3.95 and 3.65, leucocytes (×109 /L) was 5.12 and 5.34 and platelet (×109 /L) count was 83.4 and 92.5 in patients with renal involvement and without renal involvement respectively (P> 0.05). Conclusion: Renal involvement in children with dengue is not uncommon. A thorough clinical and laboratory investigations may be helpful in preventing renal involvement. Key words: Dengue haemorrhagic fever, leucocytes, serum sodium