Background: Current drug regimens grew out of empiric observations and failure of early clinical strategies. Treating tuberculosis with streptomycin, isoniazid, or pyrazinamide monotherapy in the 1950s and 1960s led to an initial favorable response that was quickly abolished by the emergence of resistance. Aim of the study: To evaluate treatment response in pulmonary tuberculosis patients. Materials and methods: The study was conducted in the Department of General Medicine of the Medical Institute. A total of 100 patients were studied. Information retrieved from the records includes socio-demographic profile of the patients, date of TB diagnosis and treatment outcome. All the patients underwent DOTS therapy for the treatment of pulmonary TB. Results: Mean age of the patients was 46.98 years. Number of male and female patients was 51 and 49 respectively. The number of PTB+ patients was 71 and the number of PTB- patients was 29. Successful treatment outcome was seen in 73% patients. Unsuccessful treatment outcome was seen in 27% patients. Conclusion: The treatment response is fairly successful. 29% patients had unsuccessful treatment response. Regular follow up of patients with unsuccessful treatment response and awareness creation through health education for rural patients in the course of treatment is vital.
Keywords: TB treatment, isoniazid, treatment outcome.