The aim of this study was to assess the effects of 8 mg dexamethasone injection into the pterygomandibular space on the postoperative sequelae of lower third molar surgery. A prospective, randomized, controlled, split-mouth study was carried out involving 52 lower third molar extractions (26 patients). Preceding surgical procedure, the study group received 2 ml of 4 mg/ml (8 mg) dexamethasone injection through the pterygomandibular space following local anaesthesia; the control group received 2 ml normal saline injection. Facial swelling, and mouth opening were evaluated. Descriptive statistics and the independent-samples t-test were used to compare the two groups at P <0.05. The swelling had reduced significantly postoperatively and there was significant increase in mouth opening on day 2 in the dexamethasone group. The pterygomandibular space injection of 8 mg dexamethasone was effective in reducing postoperative swelling, and trismus following surgical removal of lower third molar.
Keywords: dexamethasone, pterygomandibular space, third molar surgery.