Volume 8 Issue 9 (September, 2020)

Original Articles

Study of indicators of intracardial hemodynamics and structural state of the myocardium in monotherapy of patients with arterial hypertension with moxonidin
Saodat Yarmukhamedova, Feruz Nazarov, Xanuza Mahmudova, Nigora Vafoeva, Maxsuda Bekmuradova, Xudoyor Gaffarov, Doston Toirov, Murod Normatov, Suvon Yarmatov, Munira Xusainova

A total of 61 hypertensive patients with II-III degrees of increased blood pressure (WHO, 1999) aged 33 to 74 years (mean age 54.5 + 1.3) with a disease duration of 3 to 15 years were examined. Arterial hypertension of II degree occurred in 32 (52.5%), III degree - in 29 (47.5%). Among the surveyed men - 29, women - 32. All clinical and laboratory-instrumental studies were carried out on the basis of the SamMI clinic in the departments of cardiology and therapy. We carried out the selection of patients, clinical and instrumental laboratory examination, dynamic observation. The diagnosis of hypertension was made on the basis of anamnesis, clinical data and examination results according to the generally accepted program of two-stage examination of patients. Thus, we can conclude that, against the background of 12-week therapy with moxonidine in patients with arterial hypertension, there is a moderate significant regression of left ventricular hypertrophy, associated, first of all, with a decrease in the thickness of the posterior wall of the left ventricle and the thickness of the interventricular septum and positive changes in the parameters of intracardiac hemodynamics. Key words: hemodynamics, cardiology, myocardium, blood pressure, arterial hypertension

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