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Volume 2 Issue 3 (July-September, 2014)

Original Articles

ASSESSMENT OF EFFICACY OF PERCUTANEOUS AUTOLOGOUS BONE MARROW INJECTION IN CASES OF DELAYED UNION AND NON-UNION FRACTURES
Susheel Kumar Pathak, Meeta Agnihotri

Background: Cells aspirated from bone marrow are being shown to provide stimulus for osteogenesis in animal experiments and in clinical evaluation of bone graft and bone substitutes. The present study was planned to assess the efficacy of percutaneous autologous bone marrow injection in cases of delayed union and non-union fractures. Materials and methods: The study was conducted in the department of orthopedics and department of general pathology of the medical institute. In the study period, we treated 12 patients with long bone fractures with this procedure for delayed union (n=9) or non-union (n=3). Follow up after every 4-6 weeks was done to assess clinically and radiographically the rate of healing of bone. In current study, Union potential grading systems was employed. Results: Excellent union potential score was awarded to 2 patients, good score was awarded to9 patients and poor score was awarded to only 1 patient. Out of 2 patients with excellent score, union was achieved in both the patients. Out of 9 patients with good score, union was achieved in 7 patients only. Union was not observed in case of patient with poor score. Conclusion: The autologous marrow grafting is an effective method for reactivation of osteogenesis. Fracture cases with excellent union potential score had maximum probability of union.
Keywords: Bone marrow, fracture, healing, osteogenesis.

Corresponding Author: Dr. Meeta Agnihotri, Pathology, Associate professor, Career institute of Medical Sciences Lucknow, U.P., India

This article may be cited as: Pathak SK, Agnihotri M. Assessment of efficacy of percutaneous autologous bone marrow injection in cases of delayed union and non-union fractures. J Adv Med Dent Scie Res 2014;2(3):220-223.

 
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