Journal of AdvancedMedical and Dental Sciences Research

Background: Gingival Enlargement can occur as a result of the administration of certain anticonvulsants, immunosuppressants, and calcium channel blockers.Phenytoin (5-diphenylphenytoin) has been used to control seizure disorders in patients with epilepsyGingival enlargement occurs in almost 50% of patients receiving phenytoin. Aim: The present case report describes the treatment of a patient with a phenytoin-induced gingival enlargement. Case description: A 35 year old lady reported with massive gingival enlargement that covered almost her entire teeth.Her medical history revealed that she was taking phenytoin for treatment of epilepsy (100mg BID) since the age of 20.The gingival tissues appeared firm, pale pink, fibrotic with pronounced stippling. Conclusion: The report highlights that treatment of a patient with drug induced overgrowth should be carried out in a step wise manner which includes proper history, investigations, consultation with the patient’s physician, substitution of the drug, nonsurgical therapy, surgical therapy (if needed), and supportive periodontal therapy. Also, patient should be regularly reviewed for any recurrence of the enlargement.
Key words: Case report, gingival enlargement, phenytoin, drugs.

Corresponding Author: Dr.Richa Kapoor Miglani, Address: 507, Shatrunjay, Neelkanth Valley,7th road, Rajawadi, Ghatkopar (E), Mumbai 400077.

This article may be cited as: Miglani RK. Management of phenytoin induced gingival enlargement. J Adv Med Dent Scie Res 2017;5(1):99-102.