Journal of AdvancedMedical and Dental Sciences Research

Background: Lidocaine is one of the commonly used local anaesthetic solutions for dental procedures. Effect of epinephrine on the blood glucose concentration is a topic of controversy. Hence; we planned this study to investigate the effect of epinephrine containing local anaesthetic solutions on the blood glucose levels and hemodynamic parameters of the diabetic patients undergoing oral surgical procedures and further compare these findings in diabetic patients who received non- epinephrine containing anaesthetic solutions. Materials & methods: The present randomized study included assessment of the Type 2 diabetic patients who required extraction of minimum of one posterior tooth due to caries, mobility or any other minor pathologic reason as decided on the basis of radiographic and clinical diagnosis. All the patients were randomly divided into two study groups. Group 1 comprised of those diabetic patients who received plain solution of 2 percent lidocaine as local anaesthetic solution while Group 2 included diabetic patients who received 2 percent lidocaine with epinephrine at a concentration of 1: 100000. Automated sphygmomanometer was used for measurement of systolic and diastolic blood pressure (BP) at different time intervals. Assessment of all the results was done by SPSS software. Results: Non-significant results were obtained while comparing the mean blood glucose concentration in between the two study groups at initial baseline period and during the procedural period.  Conclusion: Epinephrine when delivered with lidocaine has no significant effect on the glycaemia state and the hemodynamic parameters of the diabetic patients.
Key words: Diabetic, Epinephrine, Lidocaine

Correspondence: Dr. Gaurav Singh, Reader, Department of Oral and Maxillofacial Surgery, Shree Bankey Bihari Dental College and Research Centre, Ghaziabad, Uttar Pradesh, India. Email; drgaurav2@gmail.com

This article may be cited as: Singh G, Singh P, Kumar S. Usefulness of epinephrine in local anaesthesia for monitoring hemodynamic parameters of type 2 diabetic patients undergoing tooth extraction: A prospective study. J Adv Med Dent Scie Res 2016;4(6):152-156.