Journal of AdvancedMedical and Dental Sciences Research

Background:Adverse drug reactions (ADRs) refer to unintended and harmful reactions to medications that occur at doses used for prophylaxis, diagnosis, or therapy. The present study was conducted to assess adverse drug reactions in cardiology patients. Materials & Methods:56 cardiology patients who developed ADRs of both genders were selected. They were categorized into mild, moderate, and severe ADRs, according to severity scale. The causality relationship between the drug and the effect was established using Naranjo’s ADR probability scale. Results: Out of 56 patients, males were 32 and females were 24. Severity was mild in 12, moderate in 31 and severe in 13 cases. Adverse reactions were headache in 21, hypokalemia in 14, hyperkalemia in 5, heart block in 6, bradycardia in 17, hypothyroidism in 7, HSskin reactionin 9, and hypoglycemia in 15 patients. Drugs were nitrates in 12, β blockers in 7, diuretics in 22, combined β blockers and CCBs in 8, and digoxin in 7 patients. The difference was significant (P< 0.05). Conclusion: Most of the cardiology patients had moderate severity of ADR. In maximum cases, ADRs were related with diuretics.