Journal of AdvancedMedical and Dental Sciences Research

Background: In India, breast cancer is the second most common malignancy after cervical cancer, with 20 out of every 100,000 women receiving a diagnosis. The present study evaluated the histomorphological spectrum of breast lesions in young females. Materials & Methods:135 females <30 years of age with breast lesions were enrolled. The location of the breast lesions was noted. Standard techniques were used for the histopathological evaluation, which included 10% formalin, paraffin embedding, and H&E staining. Results: Benign breast lesions found to be breast abscess in 54, accessory breast in 13, benign breast lesion in 7, lipoma in 3, fibroadenoma breast in 26, fibroadenomatosis in 3, granulomatous lesion in 2, benign fibrous histiocytoma in 2 and tubular adenoma in 3 cases. The difference was significant (P< 0.05). Malignant lesions were invasive ductal carcinoma breast in 6 and proliferative breast disease with atypia in 9 cases. The difference was significant (P< 0.05). The site of breast lesion was upper outer Quadrant in 82, lower Outer Quadrant in 10, Upper Inner Quadrant in 8, Lower Inner Quadrant in 15, Central Quadrant in 12 and Whole Quadrant in 8 cases. The difference was significant (P< 0.05). Conclusion: Rather than malignant tumors, benign lesions were present in most cases. Breast abscesses and benign breast lesions were common. The common site was in the upper outside quadrant.