Journal of AdvancedMedical and Dental Sciences Research

Background:One of the most significant pregnancy problems, gestational diabetes mellitus is linked to the morbidity and mortality of both the mother and the fetus. This study assessed increased first-trimester serum uric acid as a predictor of gestational diabetes mellitus. Materials &Methods:62 females in firsttrimester were selected. A 5-milliliter venous blood sample was obtained from pregnant women who were fewer than 12 weeks along in their gestation. After one and two hours of fasting, the venous sample was quantified and evaluated for GDM according to ADA guidelines. Results:The age group 20-25 years had 11, 26- 30 years had 29, 31-35 years had 14, 36-40 years had 6 and 41-45 years had 2 patients. The difference was significant (P< 0.05). Parity found to be primi in 36 and multi in 26. GTT was normal in 57 and positive in 5. Serum uric acid was elevated in 12 and normal in 50 cases. The difference was significant (P< 0.05). Conclusion:Elevated levels of blood uric acid during the first trimester were associated with an increased risk of gestational diabetes mellitus (GDM).