Journal of AdvancedMedical and Dental Sciences Research

Background:Subclinical hypothyroidism (SCH) is characterized by peripheral thyroid hormone levels within the normal reference range, accompanied by a slight elevation in serum thyroid-stimulating hormone (TSH) levels. The thyroid hormone is integral in regulating diverse cellular and molecular processes, exerting its influence on nearly every cell and organ, notably the heart. Our goal was to explore the prevalence of left ventricular diastolic dysfunction in individuals exhibiting subclinical hypothyroidism. Methods: A study based in a hospital was undertaken, focusing on individuals diagnosed with subclinical hypothyroidism (SCH). Participants were selected based on predefined inclusion and exclusion criteria, and they were either attending the outpatient department (OPD) or admitted to the inpatient department (IPD).Results:In instances of subclinical hypothyroidism, the average TSH levels are documented at 7.41±1.57 mU/L. The mean Free T4 levels stand at 1.57±0.38 pmol/L, while the mean Free T3 levels are reported as 4±0.81 pmol/L. Additionally, the mean left ventricular end-diastolic diameter (LVEDD) is recorded at 47.66±3.24 mm.Conclusion:The discovery of newly identified subclinical hypothyroidism is often associated with cardiovascular changes. It is crucial to promptly diagnose and address hypothyroidism to minimize its early impact on the cardiovascular system.