Journal of AdvancedMedical and Dental Sciences Research

Background:The most prevalent neoplasm affecting women is uterine fibroids, which are estimated to impact over 70% of women by the time menopause begins. The present study was conducted to assess the histopathological profile of uterine fibroids. Materials & Methods: 55 females with uterine fibroids were removed and the surgical specimen was fixed for a period of 24 to 48 hours in 10% neutral buffered formalin. A gross examination of the uterus, cervix, and bilateral adnexae was performed. Results: The age group 21-25 years had 12, 26-30 years had 28, 31-35 years had 8 and 36-40 years had 7 patients.36 patients had primigravida and 19 patients had multigravida. The common type of uterine fibroids was intramural in 11, subserosal in 16, submucosal in 24 patients and pedunculated in 4 cases. Endometrial changes were atrophic in 2, proliferative in 38, secretory in 12 and hyperplastic in 2 cases. Degenerations were none in 32, cystic in 7, red in 4, hyaline in 8 and myxoid in 3 cases. The difference was significant (P< 0.05). Conclusion:The most common pattern of endometrium observed was proliferative. Hyaline degeneration, myxoid degeneration and cystic degeneration are the common secondary changes seen in fibroid uterus.