Journal of AdvancedMedical and Dental Sciences Research

Background: The present study was conducted for assessing alteration of serum myoglobin levels in AMI patients.Materials & methods:A total of 50 AMI patients were enrolled. Complete demographic and clinical details of all the patients was obtained. In addition to standard diagnostic procedures (e.g., history, physical examination, ECG), patients agreed to providing additional experimental blood samples, which were collected from patients upon arrival and then 1 and 2 hours later. Serum blood samples were obtained from all the patients. Enzyme-linked fluorescent immunoassay was used for evaluation of serum myoglobin levels. All chemical reagents are included in a self-contained, unit dose test module. All samples were collected in the emergency department.Results:Mean myoglobin levels at 0-hour, 1 hour and 2 hours on admission was 133.5 ng/mL, 141.8 mg/mL and 113.9 mg/mL respectively. Mean alteration of mean myoglobin levels at 1 hour and 2 hours was 6.21 percent, and 114.68 percent respectively. Conclusion:Myoglobin level determinations isa sensitive test to detect acute myocardial infarction during the first 2 hours of a patient’s stay.