Journal of AdvancedMedical and Dental Sciences Research

Aim: To evaluate the clinicopathological association in chronic liver disease. Materials and method: The present study was a cross-sectional study that included analysis of clinicopathological data of 80 patients with clinically suspected chronic liver disease. A convenient sample of 80 was taken according to the total number of patients admitted to the medical wards. Adults above 15 years old with symptoms for more than 6 weeks duration with predisposing and precipitating factors, symptoms of liver disease of fewer than 6 weeks duration with significant history, and who were suspected with malignancies were included in this study. Results: The bulk of the cases (72) were identified within the age range of 30 to 69 years, with the highest concentration (24) occurring among those aged 50 to 59 years. The prevalent symptoms seen in this research were abdominal distension and loss of appetite, which were reported by 56 patients, accounting for 70% of the sample. Pain abdomen was the next most frequent symptom, reported by 44 patients (55%), followed by jaundice in 34 patients (42.5%), loss of weight in 32 patients (40%), pedal edoema in 22 patients (27.5%), fever in 20 patients (25%), oliguria in 16 patients (20%), and sleep problems in 8 patients (10%). The most prevalent clinical finding seen in the study was ascites, with a frequency of 52 cases (65%). This was followed by hepatomegaly, which was present in 48 cases (60%), icterus in 38 cases (47.5%), pedal edoema in 34 cases (42.5%), splenomegaly in 28 cases (35%), and engorged veins across the belly in 16 cases (20%). Conclusion: The prevalent manifestations seen in individuals suffering from chronic liver illness include abdominal distension and diminished appetite. The most often encountered clinical indications are ascites, hepatomegaly, abdominal discomfort, and jaundice. Histopathological testing is necessary to validate the clinical diagnosis of chronic liver disease.