Journal of AdvancedMedical and Dental Sciences Research

Aim: To investigate the risk factors associated with nasal colonisation of Methicillin Resistant Staphylococcus Aureus (MRSA) and the pattern of drug sensitivity. Material and methods: A total of 150 patients admitted in medicine ward were chosen for the study. Study population consisted of patients ≥18 years and both sexes admitted in general medicine ward during the study period. Culture was performed from anterior nares within 48 hours after admission to identify patients colonized with MRSA or MSSA. Only those patients who were negative for MRSA colonisation at the time of admission were further taken up for the study. Patients with pre-existing risk factors for MRSA colonisation were not included in the study. Results: Of total 150 subjects, 100 were male and remaining 50 were female. Mean age of study subjects was 37.99 ±6.85 years. Study subjects had a spectrum of pathology/ infections viz. Anemia 25(16.67%), Cardiac disease 18(12%), Chronic liver disease 12(10%), Diabetes 12(10%) and malaria 12(10%) etc. Out of 150 subjects, 20 (13.33%) individuals were infected with MRSA, whereas 10 (6.67%) had MSSA infection. Sterile nasal swab was reported in 100 (66.67%). MRSA carriage was common with use of steroids [OR 6.25 (95%CI 3.58-12.85)], Chronic kidney disease [OR 5.25 (95%CI 21.84-11.52)] and alcoholism [OR 3.15 (95%CI 1.05-4.63)]. Conclusion: The incidence of MRSA infection among hospitalised patients was found to be 13.33%. The risk variables that demonstrated statistical significance for MRSA were the use of steroids, the presence of Chronic renal disease, and drinking. Given the significance of each patient, it is crucial to maintain a high level of suspicion for MRSA.