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Volume 6 Issue 12 (December, 2018)

Original Articles

Prospective Evaluation of Intrathecal Isobaric Levobupivacaine 12.5 mg versus Hyperbaric Bupivacaine 10 mg for Caesarean Section: A Comparative Efficacy Study
Ayushman D Sharma

Background: Neuraxial anesthesia has gained widespread acceptance as a technique for caesarean sections. A range of local anesthetics and opioids has been employed, either independently or in conjunction. For spinal anesthesia in expectant mothers undergoing caesarean sections, there is a suggestion to use smaller opioid doses along with local anesthetics administered intrathecally. This approach is favored over epidural anesthesia because of its faster onset, superior muscle relaxation, and the reduced dosage of local anesthetics needed in caesarean procedures. It provides a dependable and high-quality block.Methods:This study, conducted in the Department of Anaesthesia, employed a prospective randomized, double-blinded design. Written informed consent was obtained from all participating parturients. A total of 180 parturients, meeting the inclusion criteria and undergoing elective caesarean sections under spinal anesthesia, were enrolled in the study.Results:All 180 patients participating in this double-blinded, randomized comparative study successfully completed the research, with no dropouts. The results are presented below, illustrating the distribution of demographic profiles in the two study groups. Importantly, there were no statistically significant differences in age, weight, or height distribution between the study groups, as evidenced by 'p' values > 0.05. Consequently, the groups were deemed comparable in terms of age, weight, and height.Conclusion:Conclusively, it appears that levobupivacaine serves as a viable and effective alternative to intrathecal bupivacaine in infra-umbilical surgeries, such as elective caesarean sections. This alternative demonstrates a reduced toxic potential while maintaining an excellent quality of analgesia.

 
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