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Volume 4 Issue 1 (January - February, 2016)

Original Articles

Exploring Cardiac Dysfunction in Chronic Liver Disease: A Comprehensive Investigation
Anand Kumar Pandey, Sharad Dayadhan Sonawane

Background: The study you mentioned has the aim of determining the prevalence of cardiac dysfunctions in patients with chronic liver disease. This is important because cardiac issues can be a significant cause of mortality in such patients, particularly those who undergo surgical procedures like Transjugular Intrahepatic Portosystemic Shunt (TIPS) or liver transplantation (LT). The objectives of the study likely involve assessing and quantifying the occurrence of cardiac dysfunctions in this patient population, which can help in understanding the risk factors and improving clinical management for better outcomes. Methods: This research was carried out as an observational investigation, involving a cohort of 100 patients diagnosed with chronic liver disease. Subsequently, these patients underwent interviews to collect their demographic information and details about their symptoms and presentation. Comprehensive physical examinations, cardiological assessments through ECG and 2D ECHO, as well as blood tests, were then conducted for all the patients. Results: The average age of patients who did not exhibit cardiac dysfunction was 40.5 years, while those with cardiac dysfunction had a higher average age of 46.26 years. Conclusion: A substantial number of patients with chronic liver disease exhibit subclinical cardiac dysfunctions. These dysfunctions carry a heightened risk of cardiovascular complications, particularly when these patients undergo surgical interventions like TIPS or liver transplantation. Consequently, there is a pressing demand for a thorough cardiac evaluation and the establishment of standardized diagnostic procedures for individuals with liver cirrhosis, particularly those undergoing TIPS or liver transplantation procedures.

 
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